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Immunity Nutrients + 13, Broccoli Sprouts, Curcumin, D and riddles- Discount Coupon

June 2009 - Print | Index


We greatly appreciate your visit to Vitamin Express. Our goal is to give you excellent personal service, fantastic product choice, nutritional information, and discounted prices.

We hope you enjoy our May newsletter.

  • Immune System 2 with our top 13 picks

  • Probiotic Ice Cream in the future?

  • New Move for Nestlé

  • Tocotrienols vs. tocopherols

  • Vitamin D and Immunity

  • Curcumin and Immunity

  • Broccoli Sprouts and Immunity

  • Broccoli Sprouts and Asthma

  • Quarterly Spring Specials

  • Discount coupon code

See our super weekly special on our home page, updated every Wednesday. Discover exceptional products at exceptional prices! Here’s our discount code for an incredible 10% OFF for over $50.00 on our already discounted prices- QH9AGB

Some riddles to humor your brain:

  • Do you know why orange juice is so smart?

  • What bone has a sense of humor?

  • What did the rib cage say to the heart?

  • He who has it doesn't tell about it. He who takes it doesn't know about it. He who knows what it is doesn't want it. What is it?

(The answers are at the end of this email.)


Best of Health to you!

The Vitamin Express Newsletter Team
Michael LeVesque
President, Vitamin Express


Immune System Nutrients #2 - Our Top Picks

In May we wrote about nutrients that aid the immune system, specifically, Vitamin C, Zinc, Propolis, Olive leaf extract, thymus, Vitamin D, Vitamin A, Alpha lipoic acid / r-lipoic acid, Beta-1,3-glucan, Colostrum, Black elderberry, and Colloidal silver.

This month is a continuation of the list. We hope you find this information helpful. References are given by our VE Health Encyclopedia Database. Additionally, we offer the mother of databases of nutritional studies that you can buy. The software is HyperHealth and it's specially priced at $39.95 instead of $79.95!

  1. Probiotics are an enormous and growing area of importance for general health and immunity. The natural protection of the gut by the implantation of friendly bacteria, by friendly transitory bacteria, and the creation of natural anti-biotic like substances such as lactic acid- aid digestion and detoxification. This provides rest and recuperation to the immune system, building stronger immunity and providing nutrients into the blood stream that dramatically aid and benefit health.

  2. DMG – Dimethylglycine is one of those amazing nutrients that have an interesting history. It all began in San Francisco with Dr. Krebs discovering what he considered a new vitamin- Vitamin B-15. In time it was banned in the US and ended up in Canada where Russia acquired it and extensively studied it naming it Aangamic. At that point the Russian Olympic team acquired it. Aangamic along with “Siberian Ginseng” were considered the magic nutrient/herb combination that helped the Russian team sweep the 1956 Olympics. Later it returned to the US and the active ingredient of the once upon time of calcium pangamate or pangamic acid was DMG. -- Simply stated DMG supports the defense mechanism of body, circulatory, cardiovascular, and neurological functions aiding muscle recovery and endurance.

  3. Betaine hydrochloride (references) is an effective way to increase stomach acid. Taken with meals it aids in protein digestion and possibly reduces food sensitivities and helps destroy pathogens and aids in reducing gas. Often it is prescribed as an aide in a wide variety of chronic disorders, such as allergies, asthma, and gallstones.

  4. B6 (references) has an endless list of attributes. However, as we grow older our ability to utilize the most common commercial form (pyridoxine HCL) is less effective because our body must convert it to pyrodoxyl-5-phosphate (P5P) the reduced form that the body utilizes. When people take supplements- especially amino acids without much benefit, frequently once they add P5P the results are dramatically improved. Therefore we highly recommend adding it to any amino acid regimen to gain full benefits.

  5. B12 (references) is another familiar nutrient with an array of accolades from researchers finding ever growing benefits from its supplemental uses. Again, the kind of B12 can make a big difference as to its effectiveness for many people. It appears that one of the best forms of B12 is methylcobalamin and dibencozide. These two active forms have become the preferred form of many nutritionists.

  6. Antioxidant enzymes are one of the most powerful tools the body has to fight inflammation and disease. The initial work of science regarding SOD (super oxide dismutase) glutathione peroxidase, methionine reductase, and catalase to name the major antioxidant enzymes has universities throughout the world doing studies and finding significant health benefits. Further down you’ll see some articles on broccoli spouts. These and other sprouts, from wheat for example, help the body to manufacture high amounts of antioxidant enzymes.

  7. CoQ10- especially ubiquinol is a remarkable enzyme nutrient that raises oxygen blood levels and promotes healing and protection of cells. Please see our newsletter dedicated to this nutrient in February 2008- CoQ10-- Ubiquinol vs. Ubiquinone.

  8. L-Carnosine (newsletter info) is one of our newer little known amino acids with huge potential and impressive research made popular mainly because it helps increase muscle strength, mass and endurance. However, it is an excellent anti-oxidant, helps protect against radiation damage, acts as a neurotransmitter, and chelates heavy metals out of the body, and reminds cells that it is time to pass on when they should (apoptosis).

  9. L-Lysine (reference) is a very familiar amino acid since its use in aiding the reduction of cold sore (herpes simplex) made it popular. However, along with Vitamin C, L-lysine was one of Dr. Linus Pauling’s (two time Nobel Laureate) favorite nutrients and with good reason. Lysine is essential for the production of the collagen protein that provides structural integrity to blood vessels.  Inadequate collagen in the blood vessels contributes to aneurysm. Researchers have proposed that optimal lysine (when used in conjunction with vitamin C) intake helps to prevent aneurysm and may aid curing even large aneurysms.

  10. N-acetyl-cysteine is one of our favorite immune aids. In our August - NAC newsletter towards the end of the newsletter is an article we presented. Basically NAC has use as an aid in most everything for the body- just look at this list- alcoholism, Alzheimer’s Disease, asthma, bronchitis, common cold, detoxification, emphysema, hepatitis, hair health, immunity, influenza, intelligence, kidney stones, noise induced hearing loss, pancreatitis, Parkinson’s Disease, and respiratory system issues. These are all uses based on studies throughout the world. Nutrients are the most studied and tested for benefits than any other form of medicine- plus the studies are often on-going and repeated in other institutions.

  11. Cat’s claw [Una de Gato, (Uncaria tomentosa)] (reference)  is studied extensively for digestive problems from gastritis, irritable bowel syndrome, and Chron’s Disease to chronic fatigue syndrome, rheumatoid arthritis, and the common cold. It has great benefits for the immune system and some reports of aiding hypertension, heart attack, and depression. It is a unique herb with a history of treatment for cancer, parasites, viral infections, diabetes, and inflammation.

  12. Fish Oils (reference) do not need to be introduced anymore. They have become one of the most popular products sold. Fish oils high in EPA (eicosapentaenoic) and DHA. (docosahexaenoic) acids are the major Omega-3 polyunsaturated fats, and are often referred to as "very long chain" polyunsaturated fats. These are “good” fats and important for immunity, brain function, and heart health- lowering triglycerides, reducing inflammation, and blood clot reduction.

  13. Anti-viral enzymes are enzymes able to dissolve almost all proteins as long as they are not components of living cells. Viruses are cell parasites consisting of nucleic acids covered by a protein film. Parasites, fungal forms and bacteria are made up of protein. Proteases can break down undigested protein, cellular debris, and toxins in the blood, sparing the immune system this task. The immune system can then concentrate its full action on defense.

Ice Cream Anyone?

Ice-cream as a vehicle for delivering probiotic strains has ‘great potential’, giving a health boost without affecting the sensory profile of ice-cream, say Brazilian scientists.

But the products must be backed up by the science and accompanied by consumer education to change eating habits of ice cream from an occasional to a frequently consumed food, according to a new review published in Food Research International.

New Direction for the BIG Food Manufacturers

Nestlé, responsible for three per cent of global food output, has stated “if we offer better nutrition, we sell more products” and it seeks ultimately to “transform itself into a nutrition, health and wellness company”. Also Danone, Coca-Cola, PepsiCo and Unilever are seeking similar strategies putting them in place at varying timetables.

The Complexity of Vitamin E

Speaking at Vitafoods 2009 in Geneva, Dr Tan explained some differences between vitamin E’s tocopherol and tocotrienol form stating, “In terms of benefits to the body, [tocotrienols] would protect a larger area of membrane in a cell, than a tocopherol that stays stationary in one place.”

“Scientists are making points to differentiate functions of tocotrienols to those of tocopherols. The three areas that delineate the tocotrienol functions from tocopherols are cancer, cardiovascular benefits, and diabetes.”

Vitamin D and Cancer Research

Vitamin D could cut the risk of pancreatic cancer in half, says a study led by researchers at Northwestern and Harvard universities.

"Because there is no effective screening for pancreatic cancer, identifying controllable risk factors for the disease is essential for developing strategies that can prevent cancer," said lead researcher, Halcyon Skinner of Northwestern.

The study found that people taking the Recommended Daily Allowance (RDA) of vitamin D (400 IU/day) reduced the risk of pancreatic cancer by 43 per cent.

"In concert with laboratory results suggesting anti-tumor effects of vitamin D, our results point to a possible role for vitamin D in the prevention and possible reduction in mortality of pancreatic cancer. Since no other environmental or dietary factor showed this risk relationship, more study of vitamin D's role is warranted," said Skinner.

The vitamin's protection is proposed to be multifaceted, by reducing the formation of blood vessels in tumors (angiogenesis), stimulating the mutual adherence of cells, and enhancing intercellular communication through gap junctions. All this adds up to stop proliferation of cancerous cells by contact inhibition.

Curcumin and Immune Health

Ayyalusamy Ramamoorthy and colleagues at the University of Michigan used solid-state NMR spectroscopy to show that curcumin physically alters the cell membrane at an atomic level.

Curcumin, the natural yellow pigment of the spice turmeric has potential benefits for reducing cholesterol levels, improving cardiovascular health, reducing the risk of Alzheimer's, and protection against cancer.

According to Ramamoorthy, curcumin can induce a negative curvature of the membrane, which would explain the potential anti-cancer activity of the compound, since other studies have shown that such changes may increase the activity of proteins such as tBid, which play an important role in apoptosis, or programmed cell death.

Using solid-state NMR spectroscopy, the Ramamoorthy and his co-workers report that molecules of curcumin insert themselves into cell membranes and make the membranes more stable and orderly. This makes the cells more resistant to infection by disease-causing microbes.

Source: Journal of the American Chemical Society
2009, Volume 131, Number 12, Pages 4490-4498, doi: 10.1021/ja809217u
“Determining the Effects of Lipophilic Drugs on Membrane Structure by Solid-State NMR Spectroscopy: The Case of the Antioxidant Curcumin”
Authors: J. Barry, M. Fritz, J.R. Brender, P.E.S. Smith, D.-K. Lee, A. Ramamoorthy

The Wonder of Broccoli Sprouts

Daily consumption of broccoli sprouts may cut Helicobacter pylori infections, and offer protection against stomach ulcers, and maybe cancer, says a new study.

Japanese men and women with H. pylori infections who consumed 70 grams a day of fresh broccoli sprouts had lower levels of the bacteria after eight weeks than men and women consuming alfalfa sprouts, according to results published in Cancer Prevention Research.

H. pylori is the only bacteria that can survive in the acidic environment of the stomach and it is known to cause peptic ulcers and gastritis.

Infection with H. pylori also causes gastritis, and infected persons are said to have a two to six-fold increased risk of developing mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric cancer compared with uninfected counterparts.

Broccoli has recently entered the public awareness as a preventive dietary agent. This study supports the emerging evidence that broccoli sprouts may be able to prevent cancer in humans, not just in lab animals,” said researcher Jed Fahey, ScD, from the Johns Hopkins School of Medicine.

Broccoli sprouts have previously been shown to reduce blood pressure in rats with hypertension due to the presence of a compound called glucoraphanin (Grn+). Sprouts are the richest source of Grn+, containing up to 50 times more than mature broccoli.

Glucoraphanin, also known as sulforaphane glucosinolate (SGS), is the precursor of sulforaphane.

Commenting on the mechanism behind the effects, the researchers noted that previous studies have reported that sulforaphane may induce cytoprotective, antioxidant, and anti-inflammatory enzymes, while other studies have reported that H pylori and sodium chloride may combine to enhance inflammation of the mucus membrane of the stomach.

Sulforaphane may be inhibiting this inflammation,” they said.

The other researchers were affiliated with Tokyo University of Science, University of Tsukuba, and Johns Hopkins University.

Source: Cancer Prevention Research
April 2009, Volume 2, Issue 4, Pages 353-360
"Dietary Sulforaphane-Rich Broccoli Sprouts Reduce Colonization and Attenuate Gastritis in Helicobacter pylori–Infected Mice and Humans" Authors: A. Yanaka, J.W. Fahey, A. Fukumoto, M. Nakayama, S. Inoue, S. Zhang, M. Tauchi, H. Suzuki, I. Hyodo, M. Yamamoto

Broccoli Sprouts—Asthma

Consumption of broccoli sprouts led to a two- to three-fold increase in levels of antioxidant enzymes linked to the protection of human airways against oxidative tissue damage, which leads to inflammation and respiratory conditions like asthma, according to findings published in Clinical Immunology.

"This is one of the first studies showing that broccoli sprouts - a readily available food source - offered potent biologic effects in stimulating an antioxidant response in humans," said lead researcher Marc Riedl from the David Geffen School of Medicine at UCLA.

"We found a two- to three-fold increase in antioxidant enzymes in the nasal airway cells of study participants who had eaten a preparation of broccoli sprouts," said Riedl. "This strategy may offer protection against inflammatory processes and could lead to potential treatments for a variety of respiratory conditions."

The study extends out understanding of the potential health benefits of broccoli, with previous studies reporting that the isothiocyanates exert powerful anti-carcinogenic activity.

"A major advantage of sulforaphane is that it appears to increase a broad array of antioxidant enzymes, which may help the compound's effectiveness in blocking the harmful effects of air pollution," said Riedl.

Source: Clinical Immunology
March 2009, Volume 130, Issue 3, Pages 244-251
“Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway” Authors: M.A. Riedl, A. Saxon, D. Diaz-Sanchez

Now for those answers to those riddles:

  1. It concentrates.

  2. humorous

  3. Got you covered

  4. counterfeit money

Don’t forget our Special Discount Code for a whopping 10% discount for an order over $50.00!!! QH9AGB Thank You for shopping Vitamin Express!

These statements have not been evaluated by the Food and Drug Administration. The products listed in this newsletter are not intended to diagnose, treat, cure, or prevent any disease. Consult with your physician before taking any of these products.